{"id":255611,"date":"2024-08-20T05:19:44","date_gmt":"2024-08-20T05:19:44","guid":{"rendered":"https:\/\/michigandigitalnews.com\/index.php\/2024\/08\/20\/inside-bavarian-nordic-the-3-3-billion-danish-vaccine-maker-with-the-worlds-only-cure-for-mpox\/"},"modified":"2025-06-25T17:12:02","modified_gmt":"2025-06-25T17:12:02","slug":"inside-bavarian-nordic-the-3-3-billion-danish-vaccine-maker-with-the-worlds-only-cure-for-mpox","status":"publish","type":"post","link":"https:\/\/michigandigitalnews.com\/index.php\/2024\/08\/20\/inside-bavarian-nordic-the-3-3-billion-danish-vaccine-maker-with-the-worlds-only-cure-for-mpox\/","title":{"rendered":"Inside Bavarian Nordic: The $3.3 billion Danish vaccine maker with the world&#8217;s only cure for mpox"},"content":{"rendered":"<p> [ad_1]<br \/>\n<\/p>\n<p>The rise of mpox is the latest health crisis that has the world scrambling to keep it under control.\u00a0<\/p>\n<div>\n<p>What started as a strain with most cases in the Democratic Republic of Congo has now spread to other parts of Africa. It has also recorded its first <a href=\"https:\/\/fortune.com\/well\/2024\/08\/15\/mpox-monkeypox-sweden-reports-1st-case-more-infectious-form\/?queryly=related_article\" target=\"_self\" aria-label=\"Go to https:\/\/fortune.com\/well\/2024\/08\/15\/mpox-monkeypox-sweden-reports-1st-case-more-infectious-form\/?queryly=related_article\" class=\"sc-93594058-0 fowfrQ\" rel=\"noopener\">European case<\/a> in Sweden, prompting the World Health Organization to declare a <a href=\"https:\/\/fortune.com\/2024\/08\/16\/mpox-clade-1b-africa-sweden-outbreak\/\" target=\"_self\" aria-label=\"Go to https:\/\/fortune.com\/2024\/08\/16\/mpox-clade-1b-africa-sweden-outbreak\/\" class=\"sc-93594058-0 fowfrQ\" rel=\"noopener\">global emergency<\/a> last week.<\/p>\n<p>Mpox, previously called Monkeypox, has proven deadly for hundreds who contracted it, including children, although a bulk of the cases have been mild so far.<\/p>\n<p>Only one company has the cure for it: Bavarian Nordic.\u00a0<\/p>\n<p>When the situation became dire last week, the Danish pharmaceutical giant donated <a href=\"https:\/\/www.reuters.com\/business\/healthcare-pharmaceuticals\/bavarian-nordic-donate-mpox-vaccine-doses-following-african-emergency-2024-08-13\/\" target=\"_blank\" aria-label=\"Go to https:\/\/www.reuters.com\/business\/healthcare-pharmaceuticals\/bavarian-nordic-donate-mpox-vaccine-doses-following-african-emergency-2024-08-13\/\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">40,000 doses<\/a> of its mpox vaccine called Imvanex to Africa\u2019s public health body. Regional groups like the European Commission said they would donate <a href=\"https:\/\/ec.europa.eu\/commission\/presscorner\/detail\/en\/ip_24_4244\" target=\"_blank\" aria-label=\"Go to https:\/\/ec.europa.eu\/commission\/presscorner\/detail\/en\/ip_24_4244\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">215,000 vaccine dose<\/a>s from their stockpile to the African health authorities.<\/p>\n<p>The drug was approved in 2022 when a health emergency over mpox was declared, and, at the time, the vaccine helped curb the outbreak to a great extent.<\/p>\n<p>There\u2019s still a need for more Imvanex (also called Jynneos) to protect those most vulnerable to a potential mpox infection. Congo, where many of the cases have been recorded, still lacks vaccines entirely.<\/p>\n<p>So, what do we know about Bavarian Nordic and how has it found itself amid the latest global health emergency?<\/p>\n<h2 class=\"wp-block-heading\">Yet another Danish pharma giant<\/h2>\n<p>Bavarian Nordic, founded in 1994, is a Copenhagen-based pharma company dedicated to <a href=\"https:\/\/www.bavarian-nordic.com\/what-we-do\/products.aspx\" target=\"_blank\" aria-label=\"Go to https:\/\/www.bavarian-nordic.com\/what-we-do\/products.aspx\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">developing vaccines<\/a>, including for Mpox, Typhoid and Rabies.\u00a0<\/p>\n<p>It\u2019s the only company that received approval from the European Union, the U.S., and other countries for its mpox vaccine.\u00a0<\/p>\n<p>It began working on its smallpox vaccine, similar to the one used for mpox, back in 2003 with the U.S. government.<\/p>\n<p>Bavarian Nordic has been instrumental in developing and supplying vaccines through other health crises, such as Ebola. For instance, in 2021 the company received a bulk purchase order from Johnson &amp; Johnson\u2019s Janssen Pharmaceutical Companies worth <a href=\"https:\/\/www.bavarian-nordic.com\/investor\/news\/news.aspx?news=6300\" target=\"_blank\" aria-label=\"Go to https:\/\/www.bavarian-nordic.com\/investor\/news\/news.aspx?news=6300\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">$28 million<\/a>.\u00a0<\/p>\n<p>Since the mpox outbreak <a href=\"https:\/\/ec.europa.eu\/commission\/presscorner\/detail\/it\/IP_22_3674\" target=\"_blank\" aria-label=\"Go to https:\/\/ec.europa.eu\/commission\/presscorner\/detail\/it\/IP_22_3674\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">two years ago<\/a>, countries and regional health departments have been building up their supply of the vaccines. The EU purchased 2 million vaccine doses at the time, approved for adult use in smallpox and monkeypox cases as the two viruses <a href=\"https:\/\/www.cdc.gov\/poxvirus\/mpox\/vaccines\/vaccine-recommendations.html\" target=\"_blank\" aria-label=\"Go to https:\/\/www.cdc.gov\/poxvirus\/mpox\/vaccines\/vaccine-recommendations.html\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">are closely related<\/a>.\u00a0<\/p>\n<p>The WHO\u2019s declaration of an emergency has caused Bavarian Nordic\u2019s shares to jump over 40%. The company\u2019s shares are up 51% since the start of the year, with its market cap at $3.28 billion.\u00a0<\/p>\n<p>Bavarian Nordic is the latest of a slew of Danish pharma companies that have gained traction recently. Novo Nordisk has seen <a href=\"https:\/\/fortune.com\/europe\/2024\/05\/01\/novo-nordisk-market-value-570-billion-bigger-than-danish-denmark-economy\/\" target=\"_self\" aria-label=\"Go to https:\/\/fortune.com\/europe\/2024\/05\/01\/novo-nordisk-market-value-570-billion-bigger-than-danish-denmark-economy\/\" class=\"sc-93594058-0 fowfrQ\" rel=\"noopener\">stratospheric growth<\/a> in the last few years following the popularity of its weight-loss and diabetes medications, Wegovy and Ozempic. Meanwhile, Zealand Pharma has emerged <a href=\"https:\/\/fortune.com\/europe\/2024\/02\/27\/novo-nordisk-competition-danish-zealand-pharma-survodutide-weight-loss-drug-trial\/\" target=\"_self\" aria-label=\"Go to https:\/\/fortune.com\/europe\/2024\/02\/27\/novo-nordisk-competition-danish-zealand-pharma-survodutide-weight-loss-drug-trial\/\" class=\"sc-93594058-0 fowfrQ\" rel=\"noopener\">as another challenger<\/a> in the obesity drug market.\u00a0<\/p>\n<p>The collective clout of Denmark\u2019s pharma industry has resulted in strong <a href=\"https:\/\/www.euronews.com\/business\/2024\/02\/20\/denmarks-gdp-soars-thanks-to-growing-pharma-sector\" target=\"_blank\" aria-label=\"Go to https:\/\/www.euronews.com\/business\/2024\/02\/20\/denmarks-gdp-soars-thanks-to-growing-pharma-sector\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">economic growth<\/a>, even causing its GDP <a href=\"https:\/\/www.bloomberg.com\/news\/articles\/2024-05-21\/denmark-s-economy-contracts-with-decline-in-pharma-production\" target=\"_blank\" aria-label=\"Go to https:\/\/www.bloomberg.com\/news\/articles\/2024-05-21\/denmark-s-economy-contracts-with-decline-in-pharma-production\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">to sway<\/a> with the performance of its drugmakers.\u00a0<\/p>\n<div class=\"wp-block-image\" style=\"margin:auto;max-width:960px\"><img loading=\"lazy\" alt=\"an elderly person seen using a machine\" loading=\"lazy\" width=\"960\" height=\"640\" decoding=\"async\" data-nimg=\"1\" style=\"color:transparent;height:auto;object-fit:cover;width:100%;background-size:cover;background-position:50% 50%;background-repeat:no-repeat;background-image:url(&quot;data:image\/svg+xml;charset=utf-8,%3Csvg xmlns='http:\/\/www.w3.org\/2000\/svg' viewBox='0 0 960 640'%3E%3Cfilter id='b' color-interpolation-filters='sRGB'%3E%3CfeGaussianBlur stdDeviation='20'\/%3E%3CfeColorMatrix values='1 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 100 -1' result='s'\/%3E%3CfeFlood x='0' y='0' width='100%25' height='100%25'\/%3E%3CfeComposite operator='out' in='s'\/%3E%3CfeComposite in2='SourceGraphic'\/%3E%3CfeGaussianBlur stdDeviation='20'\/%3E%3C\/filter%3E%3Cimage width='100%25' height='100%25' x='0' y='0' preserveAspectRatio='none' style='filter: url(%23b);' href='data:image\/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAYAAAAfFcSJAAAADUlEQVR42mO8fv1mPQAIHAMIsIR6agAAAABJRU5ErkJggg=='\/%3E%3C\/svg%3E&quot;)\" sizes=\"100vw\" srcset=\"https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=320&amp;q=75 320w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=384&amp;q=75 384w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=480&amp;q=75 480w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=576&amp;q=75 576w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=768&amp;q=75 768w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=1024&amp;q=75 1024w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=1280&amp;q=75 1280w, https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=1440&amp;q=75 1440w\" src=\"https:\/\/fortune.com\/img-assets\/wp-content\/uploads\/2024\/08\/bn_manufacturing3_300dpi-e1724072269325.jpg?w=1440&amp;q=75\"\/><figcaption>Bavarian Nordic was established in 1994. <\/figcaption><p>COURTESY OF BAVARIAN NORDIC<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">What is Bavarian Nordic\u2019s role now?<\/h2>\n<p>As the mpox crisis continues to evolve, Bavarian Nordic said it\u2019s ramping up the pace at which it produces vaccines to improve access. It has further told African health officials that it can offer 2 million doses of the drug this year and <a href=\"https:\/\/fortune.com\/europe\/2024\/08\/16\/bavarian-nordic-gearing-up-to-produce-10-million-doses-of-mpox-vaccine-as-further-imported-cases-in-europe-are-coming-who-warns\/\" target=\"_self\" aria-label=\"Go to https:\/\/fortune.com\/europe\/2024\/08\/16\/bavarian-nordic-gearing-up-to-produce-10-million-doses-of-mpox-vaccine-as-further-imported-cases-in-europe-are-coming-who-warns\/\" class=\"sc-93594058-0 fowfrQ\" rel=\"noopener\">10 million doses<\/a> by the end of 2025, according to a <a href=\"https:\/\/www.bavarian-nordic.com\/media\/media\/news.aspx?news=6970\" target=\"_blank\" aria-label=\"Go to https:\/\/www.bavarian-nordic.com\/media\/media\/news.aspx?news=6970\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">statement released<\/a> by the Danish company on Saturday.\u00a0<\/p>\n<p>It is able to produce millions of doses now because it has prepared an inventory \u201cto provide a surge capacity for potential outbreaks,\u201d it said.\u00a0<\/p>\n<p>That\u2019s not all\u2014the company has also submitted new data to request approval from the EU to extend Imvanex to adolescents <a href=\"https:\/\/www.bavarian-nordic.com\/media\/media\/news.aspx?news=6969\" target=\"_blank\" aria-label=\"Go to https:\/\/www.bavarian-nordic.com\/media\/media\/news.aspx?news=6969\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">aged 12 to 17 years<\/a>, as the recent bout of cases has impacted younger people. The U.S. Food and Drug Administration (FDA) has already granted emergency approval for the vaccine\u2019s use on adolescents.\u00a0<\/p>\n<p>\u201cThe latest data that we\u2019ve submitted is really, really important because hopefully it will extend the use of our vaccine down to adolescents,\u201d Bavarian Nordic CEO Paul Chaplin <a href=\"https:\/\/www.cnbc.com\/2024\/08\/16\/mpox-vaccine-maker-bavarian-nordic-seeks-critical-approval-for-teens.html\" target=\"_blank\" aria-label=\"Go to https:\/\/www.cnbc.com\/2024\/08\/16\/mpox-vaccine-maker-bavarian-nordic-seeks-critical-approval-for-teens.html\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">told <em>CNBC<\/em><\/a> last week.<\/p>\n<p><iframe class=\"\" frameborder=\"0\" height=\"992\" loading=\"lazy\" src=\"https:\/\/www.linkedin.com\/embed\/feed\/update\/urn:li:share:7230541485471891458\" style=\"border:none\" title=\"Embedded post\" width=\"504\"><\/iframe><\/p>\n<p>The African health authorities have asked <a href=\"https:\/\/www.politico.eu\/article\/bavarian-nordic-eu-extend-mpox-shot-imvanex-license-adolescents\/\" target=\"_blank\" aria-label=\"Go to https:\/\/www.politico.eu\/article\/bavarian-nordic-eu-extend-mpox-shot-imvanex-license-adolescents\/\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">for 10 million<\/a> vaccine doses, which will come from a combination of international donations as well as supplies from Bavarian Nordic.\u00a0Some other drug makers could chip in by providing vaccines\u2014for instance, U.S.-based Emergent BioSolutions has a smallpox vaccine that\u2019s been used to treat monkeypox. However, <a href=\"https:\/\/www.reuters.com\/business\/healthcare-pharmaceuticals\/bavarian-nordic-shares-up-45-this-week-mpox-outbreak-2024-08-16\/\" target=\"_blank\" aria-label=\"Go to https:\/\/www.reuters.com\/business\/healthcare-pharmaceuticals\/bavarian-nordic-shares-up-45-this-week-mpox-outbreak-2024-08-16\/\" rel=\"noopener\" class=\"sc-93594058-0 fowfrQ\">the latter application<\/a> hasn\u2019t been approved by the FDA yet. <\/p>\n<p>For its part, the Danish company is also planning to conduct clinical trials for those between 2 and 12 years to test the vaccine\u2019s safety as mpox hits children.\u00a0<\/p>\n<p>Despite its pivotal role in curbing the spread of mpox, Chaplin insists that it\u2019s not the \u201csole solution\u201d to the disease.<\/p>\n<p>\u201cThe international community needs to come together with Bavarian Nordic and really find a way of distributing this vaccine and containing the outbreak,\u201d he said.<\/p>\n<p>Bavarian Nordic didn\u2019t immediately return <em>Fortune<\/em>\u2019s request for comment.<\/p>\n<\/div>\n<div data-cy=\"subscriptionPlea\"><strong>Recommended Newsletter:<\/strong> Subscribe to Next to Lead, Fortune\u2019s weekly newsletter offering expert leadership strategies and insights for every stage of your career. <a href=\"https:\/\/fortune.com\/newsletters\/next-to-lead?&amp;itm_source=fortune&amp;itm_medium=article_tout&amp;itm_campaign=next_to_lead_v1081924&amp;itm_content=health_well\" target=\"_self\" aria-label=\"Go to https:\/\/fortune.com\/newsletters\/next-to-lead?&amp;itm_source=fortune&amp;itm_medium=article_tout&amp;itm_campaign=next_to_lead_v1081924&amp;itm_content=health_well\" class=\"sc-93594058-0 fowfrQ\" rel=\"noopener\">Subscribe now<\/a>.<\/div>\n<p>[ad_2]<br \/>\n<br \/><a href=\"https:\/\/fortune.com\/europe\/2024\/08\/20\/bavarian-nordic-3-3-billion-danish-only-cure-to-mpox-vaccine-maker\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[ad_1] The rise of mpox is the latest health crisis that has the world scrambling to keep it under control.\u00a0 What started as a strain<\/p>\n","protected":false},"author":1,"featured_media":255612,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[149],"tags":[],"_links":{"self":[{"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/posts\/255611"}],"collection":[{"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/comments?post=255611"}],"version-history":[{"count":0,"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/posts\/255611\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/media\/255612"}],"wp:attachment":[{"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/media?parent=255611"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/categories?post=255611"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/michigandigitalnews.com\/index.php\/wp-json\/wp\/v2\/tags?post=255611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}